An in-depth strategy Hades II Boss Fight Guide to every boss and mini-boss in Hades II – from the depths of Erebus to the peaks of Mount Olympus.
Before you even step into a boss arena, your loadout choices make all the difference. Here’s how to optimize your survival chances:
Hades II Boss Fight Guide (October 2025)
Arcana Cards to Equip
The Wayward Son: Gain health regen between rooms—ideal for staying topped up through extended zones.
The Unseen: Restores magick gradually. Crucial for spell-heavy builds.
Persistence: Grants more starting Health and Magick. A straight survivability boost.
Death: Auto-revive up to three times per run when upgraded. Arguably essential for beginners or tougher bosses.
The Lovers: Provides temporary invincibility against a few hits from Guardians—this often turns the tide during damage spikes.
Top Keepsake Choices
Luckier Tooth (Schelemeus): Grants one-time revive at 0 HP. Strongest general-purpose safety net.
Knuckle Bones (Odysseus): Weakens boss damage and starts boss encounters with reduced HP. Amazing if you’re confident with patterns but want to shorten the fight.
Evil Eye (Nemesis): Increases damage against the boss that killed you last. Perfect for revenge runs or tough matchups.
Other Smart Prep Tips
Buy armor from Charon before a boss room. Armor acts as a separate health bar that absorbs damage first.
Visit Selene’s Hex early in the run so you can unlock upgrades for it. It becomes a crucial spell tool during boss fights.
Prioritize Region-Specific Boons (marked by two golden hands). These not only tie into character quests but often boost your core stats or grant synergy-specific perks.
Always grab a Daedalus Hammer when you see one. Modifying your weapon can make or break your run.
If you lose Death Defiance, check Charon’s shop—he might offer a replacement for 200 coins.
UNDERWORLD BOSSES
1. Hecate – The Headmistress
Main Threat: High-speed spellcasting and transformation magic.
Key Tip: Dodge laterally when she tries to polymorph you. Sprint timing is crucial.
Strategy: Stay mobile, punish her after attack animations, and avoid getting caught in her delayed hex zones.
2. Skylla and the Sirens
Main Threat: Hypnotic AoEs and a rhythm-based attack pattern.
Key Tip: Focus down the drummer first—without rhythm, they’re far less threatening.
Strategy: Avoid lingering in their spell zones. Don’t let the musical theme lull you—it’s a brutal dance.
3. Cerberus
Main Threat: Multi-directional bites and lingering AoEs.
Key Tip: Target the hind head when safe—it reduces the number of simultaneous bite attacks.
Strategy: Space out attacks, retreat during growl animations, and watch for delayed eruptions after AoEs.
4. Chronos – Titan of Time
Main Threat: Arena-wide time-based mechanics and second-phase madness.
Key Tips:
Don’t predodge—watch his animations carefully.
When he starts his massive AoE countdown, stand in the safe circle or die instantly.
Destroy Tempus hourglasses if you can’t out-damage their healing.
Phase 2:
Watch the red clock hand for countdown cues.
Use traps sparingly—Chronos can weaponize them.
He retains most of his phase one kit but adds deadly time-rings and faster combos.
Strategy: Stay calm, position deliberately, and don’t rush. “Take your time” isn’t just a pun—it’s key to winning.
SURFACE BOSSES
1. Polyphemus – The Cyclops
Main Threat: Blind AoE attacks and erratic movement.
Key Tip: Don’t attack when he’s “searching.” Let him lose track of you.
Strategy: Bait his swings, reposition while he’s confused, and chip away during his wind-ups.
2. Eris – Strife Incarnate
- Main Threat: Ranged projectile spam and destructible cover.
- Key Tip: Use obstacles—but be quick; she destroys them fast.
- Strategy: Time your dash between her bursts and return fire while she reloads or moves.
3. Prometheus – Titan of Foresight
- Main Threat: Burn zones and predictive attacks.
- Key Tip: Count his aerial strikes (1-3), then move diagonally. His fire lingers—don’t re-enter zones too early.
- Strategy: Stay southwest of the burn zones and use wide AoEs to control the battlefield.
4. Typhon – Father of Monsters
- Main Threat: Huge HP pool, sweeping tongue attacks, egg spawns, and massive AoEs.
- Key Tips:
- Destroy eggs ASAP if your DPS can handle it.
- When dodging tongue swipes, stay very close to his body to avoid hitboxes.
- Position near his head to avoid horn smash impact zones.
- Strategy: This is an endurance fight. Balance aggression and mobility—don’t tunnel-vision.
UNDERWORLD MINI-BOSSES
Erebus (Zone 1)
- Shadow-spiller: Eliminate Thorn-Weepers first.
- Root-Stalker: Sprint is your best friend—don’t get rooted.
- Master-Slicer: Hit and run. Don’t overextend.
Oceanus (Zone 2)
- Hellifish: Kill minions immediately.
- Deep Serpent: Keep movements tight—don’t flail around.
- King Vermin: Use the arena traps to damage him.
Fields of Mourning (Zone 3)
- Phantom: Don’t get hit—heals from damage.
- Queen Lamia: Focus one Lamia at a time. Don’t spread damage.
Tartarus (Zone 4)
- Goldwrath: Coins are traps, not rewards.
- Verminancer: Use floor traps to lock him in place.
SURFACE MINI-BOSSES
Satyr’s Vale
- Erymanthian Boar: Lure into walls to stun it.
- Satyr Champion: Use cover, and dodge behind when it charges.
Rift of Thessaly
- Charybdis: Destroy one tentacle at a time—don’t split damage.
- The Yargonaut: Beware of ricocheting projectiles.
Mount Olympus
- Talos: Think of him as Chronos on steroids. Sprint constantly.
- Mega-Dracon: Avoid flame trails—they linger dangerously.
The Summit
- Eye of Typhon: Treat it like a Bawlder—don’t be in its path while it rolls.
- Spawn of Typhon: Dodge behind during swings. Heavy-hitting but telegraphed.
- Tail of Typhon: Stay mobile—the arena is large, so use the space to avoid corner traps.
If things are too overwhelming, God Mode is a valid option. You’ll gradually gain resistance every time you die, reducing damage taken. It doesn’t make you invincible, just more forgiving. Hades II is about myth, challenge, and progression—not perfection.
Don’t be afraid to experiment. Try different Arcana builds, weapons, and boon combos. With every death, you learn more. And when you finally take down that boss that’s been stonewalling you? That’s where the real magic of Hades II shines.